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Thalidomide-O-amido-C6-NH2 TFA

CAS No. 1950635-14-9

Thalidomide-O-amido-C6-NH2 TFA( Cereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA )

Catalog No. M26948 CAS No. 1950635-14-9

Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 42 Get Quote
5MG 69 Get Quote
10MG 102 Get Quote
25MG 170 Get Quote
50MG 250 Get Quote
100MG 392 Get Quote
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Biological Information

  • Product Name
    Thalidomide-O-amido-C6-NH2 TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
  • Description
    Thalidomide-O-amido-C6-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    Cereblon Ligand-Linker Conjugates 11 TFA | E3 Ligase Ligand-Linker Conjugates 25 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | Thalidomide-O-amido-C6-NH2 TFA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA replication| HCMV| Nucleoside Analogue
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1950635-14-9
  • Formula Weight
    544.484
  • Molecular Formula
    C23H27F3N4O8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (183.66 mM)
  • SMILES
    OC(=O)C(F)(F)F.NCCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hamada A, et al. Clinical pharmacokinetics of cytarabine formulations.Clin Pharmacokinet. 2002;41(10):705-18.
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